Zearalenone is a heat-resistant mycotoxin produced by fungi in food and animal feeds . It acts as an estrogen receptor agonist and can cause hormonal effects in animal species such as the pig . Evidence for Zearalenone effects have been observed in a wide variety of animals. The association between Zearalenone exposure and human diseases remains speculative at present; it has been considered as a possible causative agent in outbreaks of precocious pubertal changes in young children and has been suggested to have a possible involvement in human cervical cancer. [3,4]
|Solubility:||Up to 50 mM in DMSO|
|Synonyms:||Zearalenone, Mycotoxin F2, FES, Zenone, Toxin F2|
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage condition: For longer shelf life, store solid powder or DMSO solution at -20oC desiccated.
|1.||Zinedine A, et al. Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: An oestrogenic mycotoxin. Food Chem Toxicol, 2007; 45:1-18 Pubmed ID: 17045381|
|2.||Tiemann U. and Dänicke S. In vivo and in vitro effects of the mycotoxins zearalenone and deoxynivalenol on different non-reproductive and reproductive organs in female pigs: A review.Food Addit Contam, 2007; 24:306-314 Pubmed ID: 17364934|
|3.||Caloni F. and Cortinovis C. Effects of fusariotoxins in the equine species. Vet J, 2010; 186:157-161 Pubmed ID: 19837621|
|4.||Massart F. and Saggese G. Oestrogenic mycotoxin exposures and precocious pubertal development. Int J Androl, 2010; 33:369-376 Pubmed ID: 17364934|