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BAPTA-AM | Ca2+ chelator

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  • BAPTA-AM, 400x400px, png
Price:
$99.00
Catalog #:
C2278-10
Quantity:


Product Description

BAPTA-AM is a rationally-designed relative of the well-known chelator EGTA. BAPTA-AM and its analogs have a 100-fold greater affinity for Ca2+ over Mg2+, are resistant to pH changes, and are faster in uptake and release of Ca2+. [1] BAPTA-AM, the acetic acid methyl ester analog of the original BAPTA, offers greater cell permeability and is known to inactivate protein kinase C.


Technical information:

Chemical Formula:   C34H40N2O18
CAS #:   126150-97-8
Molecular Weight:   764.68
Purity:   > 98%
Appearance:   White
Chemical Name:   1,2-Bis(2-aminophenoxy)ethane-N,N,N?,N?-tetraacetic acid tetrakis(acetoxymethyl ester)
Solubility:   Up to 22 mM in DMSO
Synonyms:   BAPTA-AM, BAPTA, AM

Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.


Reference:

1. Tsien, R., New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry, 1980, 19, 2396-2404. Pubmed ID: 6770893

Other Information:

Product Specification (pdf)
MSDS (pdf)
Certificate of Analysis is available upon request.

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