Pyrintegrin is a selective, cell permeable, small molecule that was identified to help in promoting human embryonic stem cell (hESC) survival by > 30-fold. The dramatic increase in cell survival has been attributed to the protection of the cell surface protein e-cadherin from damage by Pyrintegrin.
Technical information:
| Chemical Formula: | C23H25N5O3S | |
| CAS #: | N/A | |
| Molecular Weight: | 451.54 | |
| Purity: | >98% | |
| Appearance: | Pale solid | |
| Chemical Name: | N-(cyclopropylmethyl)-4-((4-(6-hydroxy-3,4-dihydroquinolin-1(2H)-yl)pyrimidin-2-yl)amino)benzenesulfonamide | |
| Solubility: | Up to 100 mM in DMSO |
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.
Reference:
| 1. | Xu, Y., Zhu, X. et al. 2010. Revealing a core signaling regulatory mechanism for pleuripotent stem cell survival and self-renewal by small molecules. PNAS 107(18): 8129-8134. |
Other Information:
Product Specification (pdf)
MSDS (pdf)