-
BI-1356 (Linagliptin) | DPP-IV/DPP-4 inhibitor
$169.00 - $1,352.00 -
VX-765 | Caspase 1/Interleukin-converting enzyme inhibitor
$169.00 - $1,352.00 -
BIBR-1048 (Dabigatran etexilate) | Thrombin inhibitor
$169.00 - $1,352.00 -
ABT-378 (Lopinavir) | HIV-1 protease inhibitor
$89.00 - $801.00 -
TMC114 (Darunavir) | HIV-1 protease inhibitor
$169.00 - $1,352.00 -
RO4929097 | γ-secretase inhibitor
$159.00 - $1,431.00 -
Sitagliptin | DPP-IV/DPP-4 inhibitor
$89.00 - $712.00 -
YO-01027 (Dibenzazepine) | gamma-secretase inhibitor
$119.00 - $1,071.00 -
VX-950 (Telaprevir) | HCV protease inhibitor
$159.00 - $1,431.00 -
VX-478 (Amprenavir) | HIV-1 protease inhibitor
$149.00 - $1,192.00 -
RO318959 (Saquinavir) | HIV-1 protease inhibitor
$159.00 - $1,431.00 -
Rivaroxaban (Xarelto) | Protease Factor Xa inhibitor
$169.00 - $1,352.00
Protease
Proteases are a family of enzymes that conducts proteolysis by hydrolysis of the peptide bonds that link amino acids together in the polypeptide chain of proteins. These enzymes are involved in a multitude of physiological reactions from simple digestion of food proteins to highly regulated cascades (e.g., the blood-clotting cascade, the complement system, and the apoptosis pathways). Viral protease inhibitors are successful antiviral drugs that are widely used to treat HIV and HCV infections.