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Ribo-off rRNA Depletion Kit (Human/Mouse/Rat) | N406

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Product Description

Ribo-off rRNA Depletion Kit (Human/Mouse/Rat) (Vazyme, #N406) is designed to deplete rRNA (including cytoplasmic 28S, 18S, 5S rRNA, and mitochodrial 12S, 5.8S rRNA) from human, mouse, and rat total RNA preparations, while leaving mRNA and other non-coding RNA. This kit is suitable for both intact and degraded RNA samples (i.e. FFPE RNA). The obtained rRNA-depleted RNA can be used for analysis applications of mRNA and non-coding RNA (e.g. lncRNA).
Product Manual (pdf)


  • Applicable to multiple species: human, mouse, rat, etc.
  • Complete rRNA depletion: rRNA depletion rate > 99.9%.
  • Adapt to low-input RNA: Starting from 100 ng of total RNA.

When order, Cold Shipping option have to be selected, or your order may be delayed.

Selected Product Citations

  1. Huo X, et al. The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation. Mol Cell 2020, 77:368-383 PMID: 31677973
  2. Cai Z, et al. RIC-seq for global in situ profiling of RNA–RNA spatial interactions. Nature 2020, 582:432-437 PMID: 32499643
  3. Xu W, et al. METTL3 regulates heterochromatin in mouse embryonic stem cells. Nature 2021 PMID: 33505026



All components should be Store at -20°C.


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