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PS-341 (Bortezomib) | Proteasome inhibitor
$89.00 - $712.00 -
MG132 | Proteasome inhibitor
$89.00 - $712.00 -
LY2886721 | BACE inhibitor
$169.00 - $1,352.00 -
LY2811376 | BACE inhibitor
$169.00 - $1,352.00 -
BMS-477118 (Saxagliptin) | DPP-IV inhibitor
$189.00 - $1,512.00 -
BMS-232632 (Atazanavir) | HIV-1 protease inhibitor
$119.00 - $952.00 -
BMS-708163 (Avagacestat) | γ-secretase inhibitor
$169.00 - $1,352.00
Protease
Proteases are a family of enzymes that conducts proteolysis by hydrolysis of the peptide bonds that link amino acids together in the polypeptide chain of proteins. These enzymes are involved in a multitude of physiological reactions from simple digestion of food proteins to highly regulated cascades (e.g., the blood-clotting cascade, the complement system, and the apoptosis pathways). Viral protease inhibitors are successful antiviral drugs that are widely used to treat HIV and HCV infections.